Heteroaromatic Nucleophilic Substitution
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Gómez-Gil, M. Carmen ;Gómez-Parra, Vicente ;Sánchez, Félix ;Torres, TomáS
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Article
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1985
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John Wiley and Sons
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English
⚖ 528 KB
## Abstract The synthesis of several 4‐ and 5‐alkoxy‐substituted pyridazin‐3(2__H__)‐ones with hypotensive and β‐blocking activities by phase‐transfer catalysis (PTC) starting from halopyridazin‐3(2__H__)‐ones is described. The nucleophilic displacement reaction proceeds easily at the 5‐position an