Nucleophilic ring opening of lactones via SN2-type reaction with uncomplexed phenyl selenide anion

✍ Scribed by Dennis Liotta; Hector Santiesteban

• Publisher: Elsevier Science
• Year: 1977
• Tongue: French
• Weight: 176 KB
• Volume: 18
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)83510-3

✦ Synopsis

Recently, we have been interested in using phenyl selenide anion as the key reagent for the conversion of lactones to w-vinylcarboxylic acids.

1 Conceptually, our approach to this problem is shown in Scheme I.