## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Nucleophilic opening of epoxides by mixed cuprates
β Scribed by Rolf-Dieter Acker
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 162 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Terminal epoxides such as **1** react with nucleophiles (H~2~O, Cl^β^, Br^β^, N~3~^β^, and CN^β^) at the primary oxirane carbon atom to give mostly antiβMarkovnikovβtype regioisomers **5a**β**d**. The opening products of epoxide (__R__)β**1** with chloride (**5a**), bromide (**5b**) and
In the presence of LiNTf 2 , epoxides undergo ring opening with high regioselectivity and in good yield when they are treated with nucleophiles such as amines, hydrazines and thiophenol.
The use of catalytic methylrhenium trioxide (MTO) and urea hydrogen peroxide in room temperature ionic liquid for the hydroxyglycosylation with glycals in a domino fashion is reported. Excellent conversions and good selectivities for the epoxidation reaction were observed. Application to the synthes
The regioselectivity of nucleophilic ring opening of some 3,4-epoxy and 3,4-aziridino alcohols has been studied. The nucleophiles chosen were complex hydrides (LiAIH4, Red-Al and DIBAL) and Lipshutz-or Gilman-type organocuprate reagents. The C-4 substituent in the substrates was varied in order to s