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Nucleolin as Activator of Human Papillomavirus Type 18 Oncogene Transcription in Cervical Cancer

✍ Scribed by Grinstein, E.; Wernet, P.; Snijders, P. J.F.; Rosl, F.; Weinert, I.; Jia, W.; Kraft, R.; Schewe, C.; Schwabe, M.; Hauptmann, S.; Dietel, M.; Meijer, C. J.L.M.; Royer, H.-D.

Book ID
127121570
Publisher
Rockefeller University Press.
Year
2002
Tongue
English
Weight
366 KB
Volume
196
Category
Article
ISSN
0022-1007

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Human papillomavirus (HPV) DNA sequences are found in most carcinomas originating from the uterine cervix. HPV E6 and E7 oncogenes have been shown to cooperate with ras oncogenes to fully transform human epithelial cells. We investigated the effect of the Ha-ras oncogene on the transcriptional activ