DNA STRAND-BREAKS INDUCED BY THE TOPOISO
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P. Daza; J. Torreblanca; G. GarcΔ±Μa-Herdugo; F.J. Moreno
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Article
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2002
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Elsevier Science
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English
β 358 KB
## Abstract Camptothecin (CPT) and actinomicynβinduced strandβbreaks, repair and apoptosis in unstimulated human blood cells were studied using the DNA comet assay, and electrophoresis of low molecular weight DNA extracts. On the one hand, incubation of G0 leukocytes for 1h with CPT induced DNA str