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Nucleobindin 2 in human breast carcinoma as a potent prognostic factor

✍ Scribed by Shiho Suzuki; Kiyoshi Takagi; Yasuhiro Miki; Yoshiaki Onodera; Jun-ichi Akahira; Akiko Ebata; Takanori Ishida; Mika Watanabe; Hironobu Sasano; Takashi Suzuki


Book ID
108589196
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
539 KB
Volume
103
Category
Article
ISSN
1347-9032

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Nudix-type motif 2 in human breast carci
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## Abstract Nudix‐type motif 2 (NUDT2) hydrolyzes diadenosine 5β€²,5′′′‐p1,p4‐tetraphosphate (Ap4A) associated with various cellular functions. Previous studies demonstrated its regulation through estrogens, suggesting possible importance of NUDT2 in breast carcinoma. NUDT2, however, has not been exa

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I n this issue of Cancer, Dr. Roberti reviews the role of histologic grade in the prognosis of breast carcinoma and wonders why, because it is available, it has not been widely used in predicting outcome. The position of this editorial is that there must be some fundamental reason, after 100 years