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Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism

✍ Scribed by Kefei Yu; Michael R. Lieber


Book ID
116410169
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
163 KB
Volume
2
Category
Article
ISSN
1568-7864

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## Abstract Ig class switch recombination (CSR) is dependent upon the expression of activation‐induced deaminase and targeted to specific isotypes by germ‐line transcript expression and isotype‐specific factors. NF‐κB plays critical roles in multiple aspects of B cell biology and has been implicate