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Nucleic acid related compounds. 60. Mild periodinane oxidation of protected nucleosides to give 2'- and 3'-ketonucleosides. The first isolation of a purine 2'-deoxy-3'-ketonucleoside derivative

โœ Scribed by Samano, Vicente; Robins, Morris J.


Book ID
125437829
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
444 KB
Volume
55
Category
Article
ISSN
0022-3263

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Nucleic Acid Related Compounds. 94. Rema
โœ Morris J. Robins; Sanchita Sarker; Vicente Samano; Stanislaw F. Wnuk ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 692 KB

Oxidation of 2',5'-and 3',5'-0.(terr-butyldimethylsilyl)-protected ribonucleosides gave rhe corresponding 3'-keto and 2'-keto derivatives, whose complete oxidation was assayed by total release of the heterocyclic base upon treatment with tetrabutylammonium fluoride/THF. Treatment of the protected ke