Nucleic acid hydration: a volumetric perspective
β Scribed by Tigran V. Chalikian; Robert B. Macgregor Jr
- Book ID
- 104087393
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 503 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1571-0645
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π SIMILAR VOLUMES
Volumetric studies can yield useful new information on a myriad of intra-and intermolecular interactions that stabilize nucleic acid structures. In particular, appropriately designed volumetric measurements can characterize the conformation-dependent hydration properties of nucleic acids as a functi
Using high precision densimetric and ultrasonic measurements, we have determined, at 25Β°C, the apparent molar volumes V and the apparent molar compressibilities K S of four nucleic acid duplexes-namely, the DNA duplex, poly(dIdC)poly(dIdC); the RNA duplex, poly(rA)poly(rU); and the two DNA/RNA hybri
A detailed knowledge of structural and energetic aspects of water-nucleic acid interactions is essential for understanding the role of solvent in stabilizing the various helical forms of nucleic acids. In this study, computer simulation techniques have been used to predict structural properties of s