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Nucleation of calcium phosphate by surface-bound extracellular matrix

✍ Scribed by Pham, Minh Tan ;Maitz, Manfred Franz ;Reuther, Helfried ;Muecklich, Arndt ;Prokert, Friedrich ;Steiner, Gerald

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 703 KB
Volume: 71A
Category: Article
ISSN: 0021-9304
DOI: 10.1002/jbm.a.30113

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✦ Synopsis

Abstract

The native extracellular matrix (ECM) laid down on silicon and titanium surfaces by osteoblast‐like SAOS‐2 cells was exposed by selective removal of cells. This type of material surface ECM‐Si, ECM‐Ti was shown to promote the nucleation of calcium phosphate from a simulated body fluid (SBF). Microscopic and spectroscopic results revealed the effect was associated with a collagen fiber‐free extracellular matrix. © 2004 Wiley Periodicals, Inc. J Biomed Mater Res 71A: 16–24, 2004

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