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Nuclear Signaling Pathways for 1,25-Dihydroxyvitamin D3 Are Controlled by the Vitamin A Metabolite, 9-cis-Retinoic Acid

✍ Scribed by Renny T. Franceschi


Book ID
114910810
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
326 KB
Volume
51
Category
Article
ISSN
0029-6643

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## Abstract 9__‐cis__‐Retinoic acid (9cRA) and 1α,25‐dihydroxyvitamin D~3~ (1,25D) show promise as potential chemopreventive agents. We examined 9cRA and 1,25D, alone and in combination, for their potential to inhibit carcinogen (NNK)‐induced lung carcinogenesis in A/J mice. A/J mice (__n__ = 14/gr