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Nuclear receptor Nur77 suppresses inflammatory response dependent on COX-2 in macrophages induced by oxLDL

✍ Scribed by Qin Shao; Ling-Hong Shen; Liu-Hua Hu; Jun Pu; Mei-Yan Qi; Wen-Qing Li; Fu-Ju Tian; Qing Jing; Ben He


Book ID
116986139
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
855 KB
Volume
49
Category
Article
ISSN
0022-2828

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## Abstract Macrophages crosstalk with oxidized low‐density lipoprotein (oxLDL), play a critical role in the initiation, progression, and subsequently stability of atherosclerotic plaques. Statins, inhibitors of HMG CoA (3‐hydroxy‐3‐methylglutaryl coenzyme A) reductase, reduce the expression of inf