Nuclear proteins regulating transcription of the myelin basic protein gene
โ Scribed by K. Khalili; A. Steplewski; J. Gordon; S. Haas
- Book ID
- 119109017
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 153 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0165-5728
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The multiple myelin basic protein (MBP) isoforms expressed by myelinating cells are now known to have different expression patterns. The relative abundance of the isoforms containing exon II is greater early in myelinogenesis, whereas in compact myelin the isoforms lacking this exon are more abundan
The myelin basic protein (MBP) gene contains sequences located upstream of its transcription start site which play a key role in glial-specific transcription of the MBP promoter. Earlier analysis of the \(320 \mathrm{bp}\) upstream regulatory sequence of MBP has revealed multiple cis-acting regulato
Synthesis of the mouse myelin basic proteins (MBPs) ular masses of the principal variants are approximately was studied in reticulocyte lysates programmed with 21.5 kD, 18.5 kD, 17 kD, and 14 kD on SDS-polyacrylbrain mRNA in the presence or absence of brain amide gels. We have recently shown that th
## Abstract Myelin basic protein (MBP), which helps form compact myelin sheets, is a major protein expressed during oligodendrocyte (OL) differentiation. Myelin basic protein expression is regulated mainly at the transcriptional level. Previous studies showed that the transcription factor Sp1 can a