Nuclear phospholipid signaling: phosphatidylinositol-specific phospholipase C and phosphoinositide 3-kinase
โ Scribed by Dora Visnjic; Hrvoje Banfic
- Book ID
- 106109963
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 396 KB
- Volume
- 455
- Category
- Article
- ISSN
- 0031-6768
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We have previously shown that CD4 ligands inhibit interleukin-2 (IL-2) production and T cell proliferation in human peripheral CD4 + T lymphocytes, in an MHC-independent way. Two major pathways implicated in T cell activation are inhibited by binding of CD4 ligands to the CD4 molecule, i. e. Ca 2+ s