The clinical significance of vimentin intermediate filament (VIF) expression was studied in relation to other established prognostic parameters in primary breast cancer. Archival tumour samples embedded in paraffin were examined by immunohistochemistry with monoclonal antibodies (MAbs) to VIF, p53 p
β¦ LIBER β¦
Nuclear p53 Immunoreaction Associated with Poor Prognosis of Breast Cancer
β Scribed by Iwaya, Keiichi ;Tsuda, Hitoshi ;Hiraide, Hoshio ;Tamaki, Kuniyoshi ;Tamakuma, Syouetsu ;Fukutomi, Takashi ;Mukai, Kiyoshi ;Hirohashi, Setsuo
- Book ID
- 108579391
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1991
- Tongue
- English
- Weight
- 363 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0910-5050
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## Abstract In order to reveal whether differences in the type and site of __p53__ gene mutations influence the function of the gene and tumor phenotype, we examined nuclear accumulation of the p53 protein immunohistochemically, loss of the other p53 allele by restrictionβfragmentβlength polymorphi