Nuclear Matrix Proteins and Osteoblast Gene Expression
β Scribed by Joseph P. Bidwell; Marta Alvarez; Hilary Feister; Jude Onyia; Janet Hock
- Book ID
- 111486251
- Publisher
- American Society for Bone and Mineral Research
- Year
- 1998
- Tongue
- English
- Weight
- 894 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0884-0431
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Cell metabolism and function are modulated in part by cell and nuclear shape. Nuclear shape is controlled by the nuclear matrix, the RNA-protein skeleton of the nucleus, and its interactions with cytoskeletal systems such as intermediate filaments and actin microfilaments. The nuclear matrix plays a
## Abstract Cartilage oligomeric matrix protein has been implicated as an important component of endochondral ossification because of its direct effects on chondrocytes. The importance of this protein for skeletal development and growth has been recently illustrated by the identification of mutatio