✦ LIBER ✦

Nuclear magnetic resonance spectral analysis of three isomeric 2,3,5-trisubstituted N-methylpiperidines

✍ Scribed by Heleni K. Kotzamani; Ioannis K. Stamos

Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 389 KB
Volume: 32
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.1260321104

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The ^1^H and ^13^C NMR spectra of three stereoisomeric 2‐(p‐chlorophenylthiomethyl)‐3‐(3‐methoxyphenyl)‐5‐carbomethoxy‐N‐methylpiperidines were analysed in terms of configuration and solute conformation. These studies together with 2D J‐resolved, 2D‐COSY and 2D ^1^H^13^C‐correlated spectra demonstrate the existence of 2a‐3a‐5e, 2e‐3a‐5e and 2e‐3e‐5e chair conformations

📜 SIMILAR VOLUMES

13C nuclear magnetic resonance and confo

13C nuclear magnetic resonance and conformational analysis of 5-chloro-2-oxo-1,3,2-dioxathianes

✍ Jean-Pierre Gorrichon; Gérard Chassaing; Louis Cazaux 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB

Nuclear magnetic resonance spectra of ps

Nuclear magnetic resonance spectra of psychotherapeutic agents. V*—conformational analysis of 1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-ones

✍ M. C. Aversa; P. Giannetto; G. Romeo; P. Ficarra; M. G. Vigorita 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 488 KB

## Abstract The conformational analysis of biologically active lofendazam (7‐chloro‐5‐phenyl‐1,3,4,5‐tetrahydro‐__2H__‐1,5‐benzodiazepin‐2‐one) is carried out by means of lanthanide shift reagent assisted ^1^H NMR spectroscopy: the lanthanide induced shift computer simulation suggests that in deute