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Nuclear magnetic resonance investigations of calcium antagonist drugs. II: Conformational and dynamic features of verapamil in |2H6| DMSO

โœ Scribed by Antonella Maccotta; Giancarlo Scibona; Gianni Valensin; Elena Gaggelli; Franco Botre; Carlo Botre


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
481 KB
Volume
80
Category
Article
ISSN
0022-3549

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Nuclear magnetic resonance spectrometric
โœ Elena Gaggelli; Antonella Maccotta; Gianni Valensin ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 383 KB

Conformational features of diltiazem in D2O have been delineated by measuring 13C and 1H NMR parameters. The data obtained by interpretation of spin-lattice relaxation rates and 13C-[1H] nuclear Overhauser effects were used to build a model of the most probable arrangement in solution. The molecular