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Nuclear Localization of CXCR4 Determines Prognosis for Colorectal Cancer Patients

✍ Scribed by Frank M. Speetjens; Gerrit Jan Liefers; Cornelis J. Korbee; Wilma E. Mesker; Cornelis J.H. van de Velde; Ronald L. van Vlierberghe; Hans Morreau; Rob A. Tollenaar; Peter J.K. Kuppen

Book ID
107647951
Publisher
Springer Netherlands
Year
2008
Tongue
English
Weight
200 KB
Volume
2
Category
Article
ISSN
1875-2292

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## Abstract β‐catenin in its role as a nuclear signaling molecule has been implicated in prostate carcinogenesis primarily through modulation of androgen receptor activity. We defined the pattern of β‐catenin protein expression in the nuclei of normal, hyperplastic and malignant human prostate tiss