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Nuclear import by karyopherin-βs: Recognition and inhibition

✍ Scribed by Yuh Min Chook; Katherine E. Süel


Book ID
113486418
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
857 KB
Volume
1813
Category
Article
ISSN
0167-4889

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Transport of proteins into and out of the nucleus occurs through nuclear pore complexes (NPCs) and is mediated by the interaction of transport factors with nucleoporins at the NPC. Nuclear import of proteins containing classical nuclear localization signals (NLSs) is mediated by a heterodimeric prot