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Nuclear factor-κB activates dual inhibition sites in the regulation of tumor necrosis factor-α-induced neutrophil apoptosis

✍ Scribed by Masayuki Niwa; Akira Hara; Yutaka Kanamori; Daijiro Hatakeyama; Masanao Saio; Tsuyoshi Takami; Hiroyuki Matsuno; Osamu Kozawa; Toshihiko Uematsu

Book ID: 114013466
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 366 KB
Volume: 407
Category: Article
ISSN: 0014-2999
DOI: 10.1016/s0014-2999(00)00735-4

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## Abstract The nuclear factor (NF)‐κB family of transcription factors plays important roles in the regulation of many activities of neuronal cells, such as synaptic transmission, inflammation, neuroprotection, and neurotoxicity. In resting cells, NF‐κB activity is present both in the cytoplasm, as