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Nuclear DNA Sequences Present in Human Leukemic Cells and Absent in Normal Leukocytes

✍ Scribed by W. G. Baxt and S. Spiegelman

Book ID
123651335
Publisher
National Academy of Sciences
Year
1972
Tongue
English
Weight
887 KB
Volume
69
Category
Article
ISSN
0027-8424

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The Long PCR followed by the RFLP technique has been used to search for abnormally structured mitochondrial DNA (mtDNA) and specific sequence differences implicated in the pathogenesis of acute lymphoblastic leukaemia (ALL). We have studied 54 specific sites whose combinations define groups of mtDNA