Arrest of replication by mammalian DNA p
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Laura C. Bridgewater; Francis C. R. Manning; Steven R. Patierno
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Article
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1998
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John Wiley and Sons
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English
⚖ 239 KB
👁 1 views
We have previously shown that trivalent chromium, and hexavalent chromium in the presence of one of its primary in vivo reductants, ascorbate, can bind to DNA and form interstrand crosslinks capable of obstructing replication. This effect was demonstrated in vitro by using Sequenase Version 2.0 T7 D