Local ex vivo gene therapy with bone mar
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Xiao S. Zhang; Thomas A. Linkhart; Shin-Tai Chen; Hairong Peng; Jon E. Wergedal;
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Article
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2004
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John Wiley and Sons
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English
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## Abstract ## Background Bone loss in osteoporosis is caused by an imbalance between resorption and formation on endosteal surfaces of trabecular and cortical bone. We investigated the feasibility of increasing endosteal bone formation in mice by __ex vivo__ gene therapy with bone marrow stromal