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Nuclear and cytoplasmic peroxiredoxin-1 differentially regulate NF-κB activities

✍ Scribed by Jason M. Hansen; Siobhan Moriarty-Craige; Dean P. Jones


Book ID
113630333
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
518 KB
Volume
43
Category
Article
ISSN
0891-5849

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## Abstract Thioredoxin reductase (TrxR) is a flavoprotein that contains a C‐terminal penultimate selenocysteine (Sec) and has an ability to reduce thioredoxin (Trx), which regulates the activity of NF‐κB. To date, three TrxR isozymes, TrxR1, TrxR2, and TrxR3, have been identified. In the present s