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NRG1 and BDNF genes in schizophrenia: An association study in an Italian case-control sample

✍ Scribed by Alessio Squassina; Paola Piccardi; Maria Del Zompo; Alessandro Rossi; Antonio Vita; Stefano Pini; Armida Mucci; Silvana Galderisi


Book ID
116849824
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
122 KB
Volume
176
Category
Article
ISSN
0165-1781

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## Abstract Glutamatergic dysfunction is one of the major hypotheses for the pathogenesis of schizophrenia. The __GRIA1__ gene encodes for one (GluR1) of the four (GluR1–4) ionotropic AMPA receptor subunits. __GRIA1__ is a good candidate gene for susceptibility to schizophrenia since it maps in 5q3