NQO1, MPO, and the risk of lung cancer: A HuGE review
β Scribed by Kiyohara, Chikako; Yoshimasu, Kouichi; Takayama, Koichi; Nakanishi, Yoichi
- Book ID
- 120925800
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 462 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1098-3600
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## Abstract MPO participates in the metabolic activation of tobacco carcinogens such as PAHs. A frequent __MPO β463 GβA__ polymorphism in the promoter region reduces __MPO__ transcription and has been correlated with >4βfold lower benzo[__a__]pyreneβDNA adduct levels in the skin of coal tarβtreated