✦ LIBER ✦

NPY Y1 antagonists: structure–activity relationships of arginine derivatives and hybrid compounds with arpromidine-like partial structures

✍ Scribed by Iris Aiglstorfer; Anka Uffrecht; Karin Gessele; Christiane Moser; Andreas Schuster; Stefanie Merz; Barbara Malawska; Günther Bernhardt; Stefan Dove; Armin Buschauer

Book ID: 117349415
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 479 KB
Volume: 75-76
Category: Article
ISSN: 0167-0115
DOI: 10.1016/s0167-0115(98)00048-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Structure−Activity Relationships of Bisp

Structure−Activity Relationships of Bisphosphate Nucleotide Derivatives as P2Y1 Receptor Antagonists and Partial Agonists

✍ Nandanan, Erathodiyil; Camaioni, Emidio; Jang, Soo-Yeon; Kim, Yong-Chul; Cristal 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 170 KB

ChemInform Abstract: Structure—Activity

ChemInform Abstract: Structure—Activity Relationships of a Series of Benzothiophene-Derived NPY Y1 Antagonists: Optimization of the C-2 Side Chain.

✍ Thomas C. Britton; Patrick G. Spinazze; Philip A. Hipskind; Denis M. Zimmerman; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

Synthesis and structure–activity relatio

Synthesis and structure–activity relationship of N-(3-azabicyclo[3.1.0]hex-6-ylmethyl)-5-(2-pyridinyl)-1,3-thiazol-2-amines derivatives as NPY Y5 antagonists

✍ Matteo Biagetti; Colin Philip Leslie; Angelica Mazzali; Catia Seri; Domenica Ant 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 256 KB

A novel class of small molecule NPY Y5 antagonists based around an azabicyclo[3.1.0]hexane scaffold was identified through modification of a screening hit. Structure-activity relationships and efforts undertaken to achieve a favourable pharmacokinetic profile in rat are described.

Structure–activity relationships with ne

Structure–activity relationships with neuropeptide Y analogues: a comparison of human Y1-, Y2- and rat Y2-like systems

✍ Helen M Cox; Iain R Tough; Nikolaus Ingenhoven; Annette G Beck-Sickinger 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 260 KB

Structure−Activity Relationships of a Se

Structure−Activity Relationships of a Series of Pyrrolo[3,2-d]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists

✍ Norman, Mark H.; Chen, Ning; Chen, Zhidong; Fotsch, Christopher; Hale, Clarence; 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 302 KB

Synthesis and Structure—Activity Relatio

Synthesis and Structure—Activity Relationship of 4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazine Derivatives: Highly Potent and Selective AMPA Receptor Antagonists with in vivo Activity

✍ Jean-Marie Stutzmann; Marc Vuilhorgne; Serge Mignani 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 8 KB 👁 1 views