N.P.1 05 Cytogenetic aberrations in neuropathy associated with IgM monoclonal gammopathy
β Scribed by M. Eurelings; H.M. Lokhorst; N.C. Notermans; P.J. Krijtenburg; B. van Kessel; M.J. Eleveld; A.C. Bloem; J.H. Wokke; M. Poot
- Book ID
- 116792490
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 54 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0960-8966
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## Abstract We studied the frequency and clinical correlates of different IgM specificities in 75 patients with neuropathy associated with IgM monoclonal gammopathy. Patients were tested for IgM reactivity with the myelinβassociated glycoprotein, PO, neurofilaments, and tubulin by immunoblot; with
Forty cases of polyneuropathy associated with IgM monoclonal gammopathy were retrospectively studied to investigate the relevance of clinical and electrophysiological features to M-protein antibody activity. There were 26 men and 14 women; mean age was 65 Β± 11.7 years at the time of the study. Thirt