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Noxa is necessary for hydrogen peroxide-induced caspase-dependent cell death

✍ Scribed by Tomonori Aikawa; Koei Shinzawa; Nobuyuki Tanaka; Yoshihide Tsujimoto

Book ID
113621827
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
516 KB
Volume
584
Category
Article
ISSN
0014-5793

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## Abstract Oligodendrocytes, the myelin‐forming cells of the CNS, are specifically sensitive to oxidative stress and respond by the onset of programmed cell death (PCD). To further unravel the molecular events underlying their enhanced susceptibility, we have investigated whether mitochondrial dam