𝔖 Bobbio Scriptorium
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Novobiocin modulates colchicine sensitivity in parental and multidrug-resistant B16 melanoma cells

✍ Scribed by J. Nordenberg; J. Kornfeld; L. Wasserman; M. Shafran; E. Halabe; E. Beery; O. Landau; A. Novogrodsky; Y. Sidi


Book ID
112498216
Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
946 KB
Volume
120
Category
Article
ISSN
1432-1335

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## Abstract Simultaneous occurrence of resistance to many chemothera‐peutic agents, termed multidrug resistance (MDR), is a complex phenotype. MDR occurs due to several reasons, including over‐expression of a 170‐kDa membrane‐bound protein, called P‐glycoprotein (__P__‐gp), which apparently partici