Novelty-induced behavioral traits correlate with numbers of brainstem noradrenergic neurons and septal cholinergic neurons in C57BL/6J mice

Expression of the snoRNA host gene gas5

Expression of the snoRNA host gene gas5 in the hippocampus is upregulated by age and psychogenic stress and correlates with reduced novelty-induced behavior in C57BL/6 mice

✍ Ingo Meier; Laetitia Fellini; Mira Jakovcevski; Melitta Schachner; Fabio Morelli 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 604 KB

## Abstract The growth arrest specific 5 (gas5) is a noncoding protein gene that hosts small nucleolar RNAs. Based on the observation that gas5 RNA level in the brain is highest in the hippocampus and remarkably enhanced in aged mice, we tested the hypothesis that gas5 is involved in functions cont