Identification of seven novel nucleotide
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FranΓ§ois Godart; Christine BellannΓ©-Chantelot; SΓ©verine Clauin; Claudia Gragnoli
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Article
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2000
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John Wiley and Sons
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English
β 410 KB
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Maturity onset diabetes of the young (MODY) is a heterogeneous subtype of type II diabetes mellitus. To date, five MODY genes have been identified. Mutations in the hepatocyte nuclear factor-1a (HNF-1a) gene are associated with MODY3. In the present work, we implemented the HNF-1a promoter region in