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Novel translocation (2;4) with consistent involvement of 2p23 in acute nonlymphocytic leukemia (M2)

✍ Scribed by Sherif Farag; Jacqueline Challis; Joanne White; O.Margaret Garson

Book ID: 119105387
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 235 KB
Volume: 58
Category: Article
ISSN: 0165-4608
DOI: 10.1016/0165-4608(92)90132-r

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We describe a patient with acute myeloblastic leukemia (AML-M0) whose cells had a t(2;11)(p21;q23). Fluorescence in situ hybridization analysis with a probe for MLL showed that it was split, hybridizing to both the derivative 2 and 11 chromosomes. Nineteen other patients with 2p;11q translocations h