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Novel Thieno[2,3- d ][1,3]oxazin-4-ones as Inhibitors of Human Leukocyte Elastase

✍ Scribed by Gütschow, Michael; Neumann, Ulf


Book ID
120345631
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
306 KB
Volume
41
Category
Article
ISSN
0022-2623

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A series of fused thiophene derivatives, that is, representatives of thieno [2,3-d]pyrimidines, thieno[2,3-d][1,3]oxazines and thieno[2,3-d][1,3]thiazines, with the common 5-methyl-6-phenyl substitution pattern was synthesized. The target compounds, e.g., 7 or 8, were designed as cyclic analogs of e