The nuclear bile acid receptor FXR as a
✍
Michael Trauner
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
English
⚖ 216 KB
👁 2 views
Farnesoid X receptor (FXR) is a bile acid-activated transcription factor that is a member of the nuclear hormone receptor superfamily. FXR-null mice exhibit a phenotype similar to Byler disease, an inherited cholestatic liver disorder. In the liver, activation of FXR induces transcription of transpo