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Novel Terpenoids from Calocedrus macrolepis var. formosana

✍ Scribed by Chin-Lin Hsieh; Mei-Hwei Tseng; Ryh-Nan Pan; Jang-Yang Chang; Ching-Chuan Kuo; Tzong-Huei Lee; Yueh-Hsiung Kuo


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
183 KB
Volume
8
Category
Article
ISSN
1612-1872

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✦ Synopsis


Abstract

Calocetriol (1), diacetylcalocediol (2), and ferrugimenthenol (3) were isolated from the bark of Calocedrus macrolepis var. formosana. Among them, 1 and 2 are secoabietane‐type diterpenoids, and 3, with a novel C~20~ο£ΏC~10~ skeleton, is classified as a meroterpenoid. The structures of 1–3 were elucidated by spectroscopic analyses, and their biological activities were also evaluated. Compound 3 exhibited significant cytotoxic activity against human oral epidermoid carcinoma KB cells with an IC~50~ value of 9.0Β±0.1β€…ΞΌM.


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Three Novel Terpenoids from Schisandra p
✍ Sheng-Xiong Huang; Jing Yang; Wei-Lie Xiao; Yan-Ling Zhu; Rong-Tao Li; Li-Mei Li πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 German βš– 146 KB

## Abstract Three new terpenoids, pubinernoids A–C (**1**–**3**), together with six known sesquiterpenoids, were isolated from the leaves and stems of __Schisandra pubescens__ var. __pubinervis.__ The structures of the new compounds were established on the basis of extensive spectroscopic analyses,