✦ LIBER ✦
Novel tandem “ene-ISMS” methodology. Efficient and versatile assembly of a pseudomonic acid C analogue
✍ Scribed by István E Markó; Jean-Marc Plancher
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 250 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The pseudomonic acid C analogue 19 can be readily constructed using a novel tandem methodology involving, as a key-step, an ene-reaction followed by a concomitant Intramolecular Silyl-Mediated Sakurai (ISMS) cyclisatlon.