Proline-specific dipeptidyl peptidase (DPP IV) is an established enzyme known to degrade neuropeptides and peptide hormones in vertebrate tissues. DPP IV cleaves peptides at the Pro2 residue. Because several neuropeptides of the cockroach Leucophaea maderae, such as LemTRP-1 (APSGFLGVRamide), are po
Novel Tachykinin-related Peptides in the Cockroach Nervous System and Intestine : Structure, Distribution, and Actions
✍ Scribed by J. ERIC MUREN; DICK R. NÄSSEL
- Book ID
- 111392391
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 157 KB
- Volume
- 814
- Category
- Article
- ISSN
- 0890-6564
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Five isoforms of tachykinin-related peptides (TRPs), designated LemTRP-1-5, have been identified in the midgut of the cockroach Leucophaea maderae. These peptides have a conserved C-terminus hexapeptide (GFX 1 GX 2 Ramide; X 1 and X 2 are variable residues) and variable N-termini. Here, we address t
We have analyzed the relative distribution of tachykinin-related peptides (TRPs) in extracts of adult brains, thoracico-abdominal ganglia, and midguts and of the larval central nervous system of the blowfly Calliphora vomitoria using high performance liquid chromatography (HPLC) in combination with