Novel T cell subpopulations expressing CD4-1 and CD4-2 molecules in rainbow trout
✍ Scribed by Takizawa, F.; Xu, Z.; Gómez, D.; Parra, D.; Sunyer, J.O.
- Book ID
- 121466312
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 46 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1050-4648
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The pan-NK cell marker NK1.1, present in some mouse strains, is also found on a subset of TCRalphabeta+ lymphocytes termed NKT cells. These cells are primarily CD4+ or CD4-CD8- (double negative, DN), and both NKT subpopulations contain cells reactive with the MHC class I-like molecule CD1d. Murine N
## Abstract 4‐1BBL^–/–^ mice have a defect in recall CD8^+^ T cell responses to viruses, whereas CD4^+^ T cell responses to virus are unimpaired in these mice. In contrast, both CD4^+^ and CD8^+^ T cells respond to 4‐1BB ligand (4‐1BBL) __in vitro__. To clarify the role of 4‐1BB/4‐1BBL in CD4^+^ ve