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Novel Synthetic Strategy towards the Efficient Synthesis of Substituted Bis(pyrazolyl)(2-pyridyl)methane Ligands

✍ Scribed by Alexander Hoffmann; Ulrich Flörke; Markus Schürmann; Sonja Herres-Pawlis

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
402 KB
Volume
2010
Category
Article
ISSN
1434-193X

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✦ Synopsis

Abstract

A general one‐pot synthesis of new substituted heteroscorpionate ligands is presented. These mixed‐functionality ligands were obtained in a catalyzed Peterson rearrangement starting from the substituted pyrazole, thionyl chloride, and an aldehyde. Thus, the synthesis of polyfunctional tridentate ligands is enabled, and they contain, besides the two pyrazole groups, other functionalities relevant for coordination chemistry. Additionally, the steric hindrance is easily defined in the ligands by the substitution of the pyrazole rings. By combination of the versatility in donor function and steric demand, a systematic tuning of the properties of the bis(pyrazolyl)methane ligands is possible. The synthesis and full characterization of 11 bis(pyrazolyl)methane ligands are reported. Two of these were structurally characterized as well.

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