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Novel Synthetic Strategies for the Preparation of Prostacyclin and Prostaglandin Analogues — Off the Beaten Track

✍ Scribed by Neil A. Sheddan; Michael Czybowski; Johann Mulzer


Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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A novel synthesis of methyl 6-acetylsalicylate as a key synthetic intermediate for methyl 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[l-(methoxyimino) ethyllbenzoate (KIH-6127) was studied, and directed at 6-substituted pyrimidin-2-yl salicylate herbicides and their analogues. Three synthetic approaches