A2-Pyrrolin-4-ones 12 and 73, prepared from 7 -acyl-3-alkyl-1,3-dihydro-2Kindol-2-ones 7, via the corresponding 3-bromo-, 2 and 6,3-azido, 7 and 8, and 3-iminophosphorane 9 and 10, were cyclized to the corresponding pyrrolo[l,2-c]quinazoline derivatives 14 and 15.
Novel Synthesis Route for Pyrrolo[1,2-a]quinazolines.
✍ Scribed by E. S. Vostrov; D. V. Gilev; A. N. Maslivets
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 14 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract magnified image The total synthesis of chromeno[4,3,2‐__de__]quinazolin‐2‐ones, ‐quinazolines and ‐pyrrolo[2,1‐__b__]quinazolines from easily prepared 4‐methoxy‐1‐nitro‐9__H__‐xanthen‐9‐one is reported. These compounds, in which a 1,3‐diazine ring is fused to the xanthene scaffold, wer
I-(l-PyrroZidinyZlbenzenes substituted with an inino-or an in situ generated thiocarbony2 group in the 2-position rearrange upon heating to quinazotine and benzothiazine derivatives, respectively.
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