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Novel Synthesis, Reactivity, and Stereochemistry of Substituted 3-Trifluoromethyl- and 3-Perfluoroalkyl-3-phenoxyprop-2-enal

โœ Scribed by El Kharrat, Salem; Laurent, Philippe; Blancou, Hubert


Book ID
120581617
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
225 KB
Volume
71
Category
Article
ISSN
0022-3263

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Trifluoromethyl-substituted ฮ”3-imidazoli
โœ Christopher W. Derstine; David N. Smith; John A. Katzenellenbogen ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 234 KB

We describe the preparation of various 4-trifluoromethyl-substituted A3-imidazolines, which are precursors to amino acid-derived trifluoromethyl ketones. The imidazolines are prepared from ot-silylimines and trifluoroacetonitrile by a 3+2 cycloaddition, and they can be hydrolyzed in weak acid to tri