✦ LIBER ✦

Novel synthesis of thieno[2,3-b]pyridine and substituted 2-thienylthiourea derivatives as antibiotic agents

✍ Scribed by Fatima Al-Omran; Adel A. El-Khair

Publisher: Journal of Heterocyclic Chemistry
Year: 2004
Tongue: English
Weight: 94 KB
Volume: 41
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570410610

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✦ Synopsis

Abstract

Derivatives of thieno[2,3‐b]pyridine, 2‐thienylthiourea, 2‐thienylurea, 2‐thienylacetamide incorporating the 2‐phthalimidomethyl moiety have been synthesized. The synthesized compounds were then investigated for antibacterial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus. The compounds were also investigated for antifungal activity against Aspergillus niger and Fusarium oxysporium. The structures of the newly synthesized compounds have been established on the basis of their analytical and spectral data.

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