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Novel Synthesis of Substituted Cyclopropane Acetic Acid Ethyl Esters from Cyclopropyl Alkyl Ketones.

โœ Scribed by Rishan Lang Nongkhlaw; Ridaphun Nongrum; Irona Nongkynrih; Felix Mathew Vattakunnel; Bekington Myrboh


Publisher
John Wiley and Sons
Year
2005
Weight
17 KB
Volume
36
Category
Article
ISSN
0931-7597

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A Novel Stereocontrolled Synthesis of Cyclopropyl-Substituted ฮฑ,ฮฒ-Unsaturated Esters: Palladium Catalyzed Cross-Coupling of Cyclopropylboronic Acids with Bromoacrylates. -Under optimized conditions A) trans-substituted cyclopropylboronic acids (I) react in a stereocontrolled manner with ฮฑ,ฮฒ-unsatur