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Novel synthesis of monofluorocyclobutanes by the ring expansion- fluorination of cyclopropylmethanols with an amine-metal fluoride pyridinium poly(hydrogen fluoride)-complex

✍ Scribed by Shigekazu Kanemoto; Makoto Shimizu; Hirosuke Yoshioka


Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
301 KB
Volume
28
Category
Article
ISSN
0040-4039

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✦ Synopsis


Various new I-fluoro-1-alkyl(or aryl)-Z-substituted cyclobutanes were synthesized stereoselectively from I-alkyl(or aryl)cyclopropyl carbine& by the ring expansionfluorination using ('Pr)z-KHFZ-(HP), Py, and 2hydroxymethyl-l-fluorocyclobutanes