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Novel Synthesis of Heterocycles Having a Functionalized Carbon Center via Nickel-Mediated Carboxylation: Total Synthesis of Erythrocarine.

โœ Scribed by Kazuya Shimizu; Masanori Takimoto; Miwako Mori


Publisher
John Wiley and Sons
Year
2003
Weight
55 KB
Volume
34
Category
Article
ISSN
0931-7597

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Addition of the lithium enolate of acetic acid esters to 1-chlorovinyl p-tolyl sulfoxides, which were derived from ketones and chloromethyl p-tolyl sulfoxide in three steps in good yields, gave carboxylic acid esters having a quaternary carbon at the 3-position, and chlorine and sulfinyl groups at t