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Novel synthesis of furan-2-acetic esters by palladium-catalysed oxidative cyclization-alkoxycarbonylation of (Z)-2-En-4-yn-1-ols

✍ Scribed by Bartolo Gabriele; Giuseppe Salerno; Francesca De Pascali; Giuseppe Tomasi Scianò; Mirco Costa; Gian Paolo Chiusoli


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
185 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis


Furan-2-acetic esters are obtained in good yields by direct oxidative cyclization-alkox~.'carbonylation of (Z)-2-en-4-yn-l-ols. bearing both an alkyl or an aD'l substituent a to the hydrox3' group, in the presence of catalytic amounts of palladium iodide in conjunction with potassium iodide at 50-70°C and 100 atm of a 9:1 mixture of carbon monoxide and air.


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