Novel synthesis of furan-2-acetic esters by palladium-catalysed oxidative cyclization-alkoxycarbonylation of (Z)-2-En-4-yn-1-ols
✍ Scribed by Bartolo Gabriele; Giuseppe Salerno; Francesca De Pascali; Giuseppe Tomasi Scianò; Mirco Costa; Gian Paolo Chiusoli
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 185 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Furan-2-acetic esters are obtained in good yields by direct oxidative cyclization-alkox~.'carbonylation of (Z)-2-en-4-yn-l-ols. bearing both an alkyl or an aD'l substituent a to the hydrox3' group, in the presence of catalytic amounts of palladium iodide in conjunction with potassium iodide at 50-70°C and 100 atm of a 9:1 mixture of carbon monoxide and air.
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