Novel Synthesis of Functionalized Cyclobutane Derivatives via Intramolecular Conjugate Addition of Alkenyltrimethylstannane Functions to α,β-Alkynic Esters Mediated by Copper(I) Chloride
✍ Scribed by Piers, Edward; Boehringer, Eva M.; Yee, James G. K.
- Book ID
- 126993061
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 54 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3263
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AbstractÐA new copper(I)-mediated method for effecting intramolecular conjugate addition of alkenyl functions to a,b-unsaturated ketone systems is reported. Treatment of the substrates 14, 15, 19±21, 22 and 23 with 2.5 equiv. of CuCl in DMF at room temperature affords excellent yields of the corresp
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